产品货号：
Z32396
中文名称：
CRM1/XPO1抗体
英文名称：
Anti-CRM1/XPO1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CRM1/XPO1 Antibody |
| 指标别名 | CRM1;Exp1;Exportin 1;XPO1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | XPO1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human CRM1 Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs.In the nucleus,in association with RANBP3,binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP).Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. |
| 实际分子量 | 123KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Exportin 1 (XPO1),also known as chromosomal maintenance 1 (CRM1),is an eukaryotic protein that mapped to human chromosome 2p16 by fluorescence in situ hybridization.This protein mediates leucine-rich nuclear export signal (NES)-dependent protein transport.It specifically inhibits the nuclear export of Rev and U snRNAs.Additionally,this protein is involved in the control of several cellular processes by controlling the localization of cyclin B,MPAK,and MAPKAP kinase 2.It also regulates NFAT and AP-1. |
| Uniprot ID | O14980 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：CRM1/XPO1抗体，CRM1抗体，XPO1单抗，Anti-CRM1/XPO1 Antibody